Physical properties of the skin in the Ehlers-Danlos syndrome.

نویسندگان

  • R Grahame
  • P Beighton
چکیده

*Read to the Heberden Society on February 14, 1969. tPresent address: Department of Physical Medicine, Guy's Hospital, London,9.E.pu Preet address: ohns Hopkins Hospital, Baltimore. circus exhibitionists. One gentleman made his name by his ability to place six golf balls in his mouth at the same time (Duperrat, 1965). Another well-known clown could touch his nose with his bottom lip. A photograph of an "Elastic Lady", which was found in a Hampstead fairground peepshow, is shown in Fig. 2. Pride of place must go to the Spaniard, George Albes, who in 1657 demonstrated before the physicians of the Academy of Leiden "the extraordinary dilatability of his skin, which could be stretched to half an ell"* (van Meekeren, 1682). In a contemporary portrait he is depicted pulling up the skin of his chest to touch his chin.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Ehlers-Danlos syndrome: type VI A – kyphoscoliosis; a case report

Ehlers-Danlos syndrome (EDS) is a clinically heterogeneous groupof inherited disorders with ten different types, all involving agenetic defect in collagen and connective-tissue synthesis andstructure that affecting the skin, joints, and blood vessels. EDStype VIA, a very rare kyphoscoliotic type, is autosomal recessiveand clinically characterized by soft extensible skin, laxity ofjoints and kyp...

متن کامل

An Iranian family with cutis laxa and classic Ehlers-Danlos syndrome

Ehlers-Danlos syndrome (EDS) is a heterogenous group of inherited disorders of connective tissue characterized by fragility of the skin and blood vessels, hyperextensibility of the skin and joint hypermobility. Cutis laxa is characteized clinically by lax, pendulous skin and histologically by loss of elastic tissue in the dermis. There are some reports of coexistence of cutis laxa with ot...

متن کامل

Ehlers-Danlos Syndrome (TYPEI) with Mental Retardation -an Unusual Association (Reports on Two Brothers)

Ehlers Danlos syndrome (EDS) is an inherited connective tissue disease due to impaired collagen metabolism. Joint hypermobility and skin hyper extensibility are the major findings. Six types of EDS are recognized. Type I or Gravis type is characterized by skin hyperextensibility, joint hypermobility, skin splitting autosoml dominancy inheritance, preterm premature rupture of membrane (PPROM) an...

متن کامل

اهمیت شناخت سندرم Ehlers Danlos بوسیله دندانپزشکان: گزارش یک مورد

This syndrome is a genetical disorder with symptoms result from deficit in the formation of connective tissue, especially collagen fiber biosynthesis. In these patients, there is hyperelasticity and fragility of the skin and mucosa. Injuries sever bleeding, internal bleeding and hemartrosis may be seen in these patients. Wounds leave scars after healing. There is recurrent dislocation of the jo...

متن کامل

Skin ultrastructural similarities between Fibromyalgia and Ehlers-Danlos syndrome hypermobility type

Fibromyalgia (FM) and hypermobility type Ehlers-Danlos syndrome (EDSH) share a series of common clinical signs. A clinical distinction between both diseases is occasionally difficult to be established. The physical changes observed in the mechanical properties of skin and joints do not distinctly distinguish these disorders. In addition, similar ultrastructural dermal changes are observed in bo...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Annals of the rheumatic diseases

دوره 28 3  شماره 

صفحات  -

تاریخ انتشار 1969